After Alpha Flight and Department H was officially suspended, Weapon: P.R.I.M.E. was assigned by General Clarke (Department H's former military liaison) to replace them. Under the control of General Clarke, Weapon P.R.I.M.E. was ordered to remove Northstar from the public eye, compounded by his apparent murder of a tabloid reporter. Weapon: P.R.I.M.E. tracked Northstar down, first in Ibiza, then in Russia, finally giving up in New Orleans under orders from their leader, Tigerstryke who came to believe in Northstar's innocence.
- Various high-tech weapons and gadgets
- The original Weapon: P.R.I.M.E. was to be led by Kane but when S.H.I.E.L.D. wanted to take down Cable, agent Bridge brought them in to help and became field commander of the team.
- 11 appearance(s) of Weapon P.R.I.M.E. (Earth-616)
- 4 mention(s) of Weapon P.R.I.M.E. (Earth-616)
- 2 image(s) of Weapon P.R.I.M.E. (Earth-616)
- 8 member(s) of Weapon P.R.I.M.E. (Earth-616)