Sue was my life. She was beauty itself, grace, everything that I never was, everything that had meaning. And she's dead... dead because of Annihilus and his stupid antics-- his brute savagery. And because of time. 
- —Reed
Appearing in "What If Susan Richards Had Died in Childbirth?"
Featured Characters:
- The Fantastic Four (First appearance)
- Mister Fantastic (First appearance) (Death)
- The Thing (First appearance)
- The Human Torch (First appearance)
- Invisible Woman (First appearance) (Death)
- Crystal (First appearance)
Antagonists:
- Annihilus (First appearance; dies)
- A Spatial Predator
- Doctor Doom (First appearance)
- Negative Zone Borers
Other Characters:
- Uatu the Watcher
- Sue's Doctor
- Franklin Richards (Mentioned)
- The Avengers (First appearance)
- Captain America (First appearance)
- Hawkeye (First appearance)
- The Scarlet Witch (First appearance)
- Quicksilver (First appearance)
- Giant Man (First appearance)
- Wasp (First appearance)
- Thor (First appearance)
- Iron Man (First appearance)
- Black Widow (First appearance)
- Doctor Strange (First appearance)
- Alicia Masters (First appearance)
- Funeral Attendees from Chicago
- Atlanteans
- The X-Men (First appearance)
- Cyclops (First appearance)
- Marvel Girl (First appearance)
- Angel (First appearance)
- Beast (First appearance)
- Iceman (First appearance)
- Willie Lumpkin (First appearance)
- Hercules (First appearance)
- The Black Panther (First appearance)
- Spider-Man (First appearance)
- Daredevil (First appearance)
- Inhumans
- Black Bolt (First appearance)
- Medusa (First appearance)
Locations:
- Earth-8312 (Reality)
- The Baxter Building
- The Negative Zone
- Coloumbia University (Main story and flashback)
- An Ice Cream Parlor (Main story and flashback)
- Reed's Library
- Annihilus' Planetoid
Items:
- The Cosmic Control Rod
- Anti-Gravity harnesses
- Reed's Negative Zone Portal
- A Pressor Beam
Vehicles:
- Annihilus' Ship
- Reed's Sky-Cycle
- The Fantasti-Car MK II
- A Negative Zone Explorer
Synopsis for "What If Susan Richards Had Died in Childbirth?"
Sue dies giving birth to Franklin, who is never seen. Reed takes his revenge on Annihilus for delaying his return to his wife before she passed, killing himself and Annihilus in his grief.