Dr. Wilma Calvin is a respected biochemist. She lost her husband, Henry, while her son, Percy, was still a child.
She was the senior advising scientist on Project: Gladiator, a S.H.I.E.L.D.-backed project to recreate the Super Soldier Serum that created Captain America. Her team for this consisted of Dr. Ted Sallis, chemist Bobbi Morse, Dr. Paul Allen, a medical doctor named Wendell, and a technician named Jim.
Between Sallis's girlfriend, Ellen Brandt, and Allen, who was really an agent of A.I.M., the project was sabotaged, transforming Sallis into the Man-Thing. The locals considered Calvin a "witch-woman" for creating monsters in her laboratory. Calvin thought it was obvious that Man-Thing was what remained of Ted Sallis, but a local shot her in the back.
Dr. Wendell cared for her until Dr. Allen killed him and kidnapped her because of her knowledge of the serum. Allen met his death at Man-Thing's hands. She was brought back to her home in New York City by Ka-Zar and Dr. Morse. However, she was left unguarded and taken away by her son "Vinnie" (Percy), who was forced to work for the Pusher. Eventually, Percy intervened and helped Ka-Zar defeat the Pusher, winding up in a full body cast. Although there was concern that Wilma would go into shock, she accepted things as they were and recovered.
Wilma was ultimately killed by Percy, who used his mother's death in order to attract the attention of Bobbi Morse, who had recently been injected with a combination of the Super Soldier Serum and the Infinity Formula, in order to capture her and use her for his research.
- 9 Appearances of Wilma Calvin (Earth-616)
- 1 Minor Appearances of Wilma Calvin (Earth-616)
- Media Wilma Calvin (Earth-616) was Mentioned in
- 1 Images featuring Wilma Calvin (Earth-616)
- Quotations by or about Wilma Calvin (Earth-616)
- Character Gallery: Wilma Calvin (Earth-616)
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