Zakim Karzai was an Afghani terrorist and one of several men responsible for the murder of scientist Ho Yinsen. Fifteen years after Yinsen's death, Karzai was serving in Southern Iraq with another of Yinsen's murderers, Aftaab Lemar. The son of Ho Yinsen, wishing to avenge his father's death, took control of Tony Stark as well as his bio-enhanced Extremis Armor and flew to Iraq. Iron Man grabbed both Karzai and Lemar, flew them high into the sky, then let them fall to their deaths.[1]

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